![]() Additionally, lower absolute number of lymphocyte and their subpopulations CD3+ T cells, CD4+ T-helper cells and CD8+cytotoxic T-cells, were observed in infected subjects. Infected subjects exhibited significantly higher levels of inflammatory cytokines, including IL-6, IL-8, IL-10, IL-1β and TNF-α, than non-infected subjects after CPB. Inflammatory cytokines, serum CRP and PCT values were measured in plasma, additionally, circulating total leucocyte and lymphocyte subpopulations were counted. Among them, 9 subjects had an early postoperative infection, and 32 subjects were period-matched without infection. MethodsĪ retrospective analysis including 41 children under 2 years old underwent CPB. ![]() ![]() This study aims to investigate the association between lymphopenia following CPB and early postoperative infection in children. Children who undergo CPB operations are at an elevated risk of infection due to immunosuppression. ![]()
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